Searchable abstracts of presentations at key conferences in endocrinology

ea0015p329 | Steroids | SFEBES2008

Use of placebo for withdrawal of steroid therapy is contraindicated in adrenal insufficiency

White Katherine , Elliott Alyson , Hawks Noel , McEntegart Mary

Adrenal insufficiency (AI) patients who are deprived of regular steroid replacement therapy rapidly become unwell. However, the interval for which AI patients might safely be withdrawn from steroid medication for clinical purposes, such as re-assessment of adrenal reserve, is largely a matter of speculation, since it would be difficult to construct an ethical trial on this matter. Valuable insights into this dilemma can be gained from the case studies of an early clinical rese...